Figure 1 from Astrocyte development and heterogeneity Biology Diagrams

Figure 1 from Astrocyte development and heterogeneity Biology Diagrams Astrocytes are the most abundant cell type in the central nervous system and have diverse functions in blood-brain barrier maintenance, neural circuitry formation and function, and metabolic regulation. To better understand the diverse roles of astrocytes, we will summarize what is known about astrocyte development and the challenges limiting

Introduction. Astrocytes comprise a diverse population of cells responsible for a broad array of functions in the nervous system. Nevertheless, our understanding of fundamental principles of astrocyte biology, including their development, remains far behind that of other glial cell populations in the nervous system, including oligodendrocytes and Schwann cells (Jessen and Mirsky, 2005). Astrocytes are the most abundant cell type in the central nervous system and have diverse functions in blood-brain barrier maintenance, neural circuitry formation and function, and metabolic regulation. These parental cells exhibited astrocyte characteristics, including morphology, gap junction connectivity, and expression of astrocyte

Molecular and metabolic heterogeneity of astrocytes and microglia ... Biology Diagrams

The GO terms for cluster 5 are related to cell cycle and proliferation processes, A primary objective of this study was to understand the distinctive characteristics of WM astrocytes. Unlike Astrocytes are the most plentiful cell type in the central nervous system (CNS) and perform complicated functions in health and disease. It is obvious that different astrocyte subpopulations, or activation states, are relevant with specific genomic programs and functions. In recent years, the emergence of new technologies such as single-cell RNA sequencing (scRNA-seq) has made substantial

Gene expression in neonatal astrocytes is characteristics and these cells are considered more activated than their adult counterparts On the other hand, the neonatal astrocytes express more genes that are important for the regulation of the cell cycle, including DNA binding and apoptosis, regulation of cell adhesion, cytoskeleton Astrocytes are a subtype of glial cells that make up the majority of cells in the human central nervous system (CNS). They perform metabolic, structural, homeostatic, and neuroprotective tasks such as clearing excess neurotransmitters, stabilizing and regulating the blood-brain barrier, and promoting synapse formation.[1][2][3][4] Unlike neurons and other cells in the nervous system, they do The source of newly divided scar-forming astrocytes is not well established, and may include mature astrocytes that re-enter the cell cycle as well as progenitor cells in the local parenchyma or in the periventricular regions [30, 33, 37, 77, 133, 141, 226]. Molecular triggers and regulators of reactive astrogliosis and glial scar formation